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GLP-1 Medical Weight Loss
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GLP-1 Weight Loss Program in NYC

GLP-1 Weight Loss

Lose
fat, not muscle. 

Lose fat while protecting the muscle you want to keep, clinically managed and tracked with DEXA so you can see exactly what is changing.

Starts with a DEXA and a consult
★ 4.8 on Google3 NY locationsMedical-grade carePrivate-pay, no insurance
✓
Every therapy starts the same way.GLP-1 Medical Weight Loss begins with a DEXA scan and a full blood panel. We measure first, then we treat. No guessing, no generic protocol.
Book your baseline →
Why do it here

Lose fat, keep the muscle

1

A DEXA baseline first

Most GLP-1 programs never measure. We know exactly how much of you is fat and how much is muscle before day one.

2

We protect your lean mass

Rapid weight loss costs you muscle. Quarterly DEXA proves whether the weight coming off is fat, and we adjust if it is not.

3

Medically supervised

Dosing, side effects and titration handled by clinicians who see your labs.

4

A plan for after

Nutrition, protein targets and training so the result holds when you come off.

The GLP-1

Everything in one picture

What it is, what is included and what to expect, in one view.

GLP-1 Medical Weight Loss
What it is

Fat loss, clinically managed

GLP-1 medication can be a powerful tool for stubborn fat that has not moved with effort alone. At Prefusion it is always physician-managed and always measured.

DEXA first
We set your baseline before we begin.
Muscle-safe

Keep what you built.

Quarterly DEXA confirms the loss is fat.

What is included

What you get

✓Baseline DEXA scan and medical consult
✓A physician-managed GLP-1 plan
✓Follow-up DEXA tracking so loss is fat, not muscle
✓Nutrition guidance to protect lean mass
✓Member pricing when you join the membership
MD led
Physician managed every step.
What to expect

Your visit, step by step

1
Start with a DEXA and consultWe set your baseline and review whether GLP-1 is right for you.
2
Begin your managed planIf it fits, a physician prescribes and manages your therapy.
3
Track with DEXAFollow-up scans confirm you are losing fat and holding muscle.
Go deeper

The detail, made simple

Why we track with DEXA

Rapid weight loss can cost you muscle if it is not managed well, and the scale will never tell you the difference.

Pairing GLP-1 with DEXA means we can see your body composition change and protect the lean mass that keeps your metabolism strong.

Why we track with DEXA

What you get

✓Baseline DEXA scan and medical consult
✓A physician-managed GLP-1 plan
✓Follow-up DEXA tracking so loss is fat, not muscle
✓Nutrition guidance to protect lean mass
✓Member pricing when you join the membership
GLP-1 Medical Weight Loss

Your visit, step by step

1. Start with a DEXA and consult. We set your baseline and review whether GLP-1 is right for you.

2. Begin your managed plan. If it fits, a physician prescribes and manages your therapy.

3. Track with DEXA. Follow-up scans confirm you are losing fat and holding muscle.

Is this right for you?

✓You have stubborn fat that has not responded to effort
✓You want a clinically supervised approach
✓You want to keep your muscle while losing fat
✓You value measured progress over the scale alone
Who it is for
Benefits

Benefits of GLP-1 Weight Loss Therapy

FDA-approved and proven

Semaglutide and tirzepatide are FDA-approved and backed by large clinical trials.

Fat loss, not muscle loss

DEXA tracking and dietitian support keep the loss fat, protecting the muscle that keeps your metabolism strong.

Targets visceral fat

Reduces the deep abdominal fat linked to heart disease and insulin resistance, measured by DEXA.

Appetite control without willpower

The medication works on your hunger signals, so cravings stop running the show.

Better blood sugar

Improves insulin sensitivity and stabilizes blood sugar, benefits well beyond the scale.

Medically supervised

Licensed providers adjust your plan every 90 days on your real data.

FAQ

Good to know

What medications are used in the GLP-1 program?
The GLP-1 medical weight loss program uses FDA-approved medications such as semaglutide and tirzepatide, which help regulate appetite, improve metabolic function, and support fat loss while preserving lean muscle mass.
Will I lose muscle while on GLP-1 medication?
GLP-1 therapy here is paired with DEXA tracking and dietitian support, so the goal is fat loss while protecting lean muscle. Follow-up scans show exactly what is changing, and we adjust your plan if the loss is not coming from fat.
How often will I be monitored?
You have monthly clinical check-ins, and follow-up DEXA scans track your body composition, so your fat loss stays safe and on track toward your health goals.
Can I stop the medication in the future?
Yes. Once you reach your weight loss goals and your metabolic health has improved, you can gradually reduce or stop the medication under medical supervision.
Is this program medically supervised?
Yes. The GLP-1 program is guided by licensed medical providers, with dietitian support along the way.
How long will it take to see results from GLP-1 therapy?
Many clients begin to see noticeable fat loss and better metabolism within a few weeks. Full results build over several months, depending on your goals and your commitment to the program.
Do I need to follow a specific diet while on GLP-1 medication?
Yes. For the best fat loss and muscle preservation, you follow a healthy eating plan personalized to your needs, with nutrition guidance and protein targets from our team.
Can GLP-1 therapy help with other health conditions?
Beyond weight loss, GLP-1 therapy can improve insulin sensitivity and help stabilize blood sugar, and it targets the deep abdominal (visceral) fat that DEXA measures. Your provider will talk you through what this means for your own health.
Will I regain the weight after stopping GLP-1 medication?
Keeping the weight off depends on continuing a healthy lifestyle. The program focuses on sustainable fat loss, metabolic health and muscle retention, to help you maintain your results after stopping the medication.
Is GLP-1 therapy safe for long-term use?
How long you stay on GLP-1 therapy is decided with your provider. At Prefusion it is always medically supervised, with regular lab work and body composition tracking, so your plan can be adjusted or tapered when the time is right.
Keep exploring

Related at Prefusion

Real reviews

Rated 4.8 on Google

★★★★★ 4.8 · 55 Google reviews from New Yorkers who stopped guessing and started measuring
★★★★★

“Ten out of ten experience, super knowledgeable staff. I did the DEXA scan, RMR and VO2 max, then they sat me down and went through all of it, making sure I understood what my numbers meant and what to do next.”

Allen Y. · Google review
★★★★★

“Bryan and the team have been consistently awesome to me and my friends. You get your raw scores, it is explained to you in person and on a handy app, and you leave with real recommendations on how to improve.”

Andrew H. · Google review
★★★★★

“Ten out of ten experience, super knowledgeable staff. I did the DEXA scan, RMR and VO2 max, then they sat me down and went through all of it, making sure I understood what my numbers meant and what to do next.”

Allen Y. · Google review
★★★★★

“Bryan and the team have been consistently awesome to me and my friends. You get your raw scores, it is explained to you in person and on a handy app, and you leave with real recommendations on how to improve.”

Andrew H. · Google review
★★★★★

“Matt was an incredible consultant. The optimization package finally gave me something concrete and efficient to work with. It has done a full 360 for my plans going forward.”

Khao · Google review
★★★★★

“Training for a race, I came in for the optimization package. Between the DEXA scan, RMR and VO2 testing, I have full clarity on where my health is and what I need to improve.”

Elias Z. · Google review
★★★★★

“Matt was an incredible consultant. The optimization package finally gave me something concrete and efficient to work with. It has done a full 360 for my plans going forward.”

Khao · Google review
★★★★★

“Training for a race, I came in for the optimization package. Between the DEXA scan, RMR and VO2 testing, I have full clarity on where my health is and what I need to improve.”

Elias Z. · Google review
★★★★★

“I am a big numbers girl, so seeing the detailed data from my DEXA scan and VO2 max was super helpful for my running goals. They guided and supported me through the whole process.”

Amy D. · Google review
★★★★★

“Super comprehensive results, all the detail on the app and a clear explanation in person. We loved it so much we bought a 6-pack so we can track our health journey.”

Pallavi P. · Google review
★★★★★

“I am a big numbers girl, so seeing the detailed data from my DEXA scan and VO2 max was super helpful for my running goals. They guided and supported me through the whole process.”

Amy D. · Google review
★★★★★

“Super comprehensive results, all the detail on the app and a clear explanation in person. We loved it so much we bought a 6-pack so we can track our health journey.”

Pallavi P. · Google review
What it is

What is GLP-1 Therapy?

GLP-1 therapy is a medical weight loss treatment that uses FDA-approved medications to mimic a naturally occurring hormone in your body called glucagon-like peptide-1 (GLP-1). This hormone plays a critical role in regulating appetite, blood sugar levels, and how your body processes and stores fat.

At Prefusion Health in NYC, GLP-1 therapy goes beyond simply prescribing medication. Every program is physician-managed, data-driven, and built around your unique biology, with DEXA tracking so your fat loss is measured and your lean muscle is protected along the way.

Book your entry visit →
GLP-1 therapy at Prefusion Health in NYC
Why Prefusion

Why Choose Prefusion Health for Your Weight Loss Program

1

Personalized GLP-1 weight loss plan

Your plan is built on a DEXA body composition scan and a full blood panel, so the program targets fat while preserving muscle, with long-term results in mind.

2

FDA-approved medications

The medications we use, semaglutide and tirzepatide, are FDA-approved and backed by large clinical trials. Every prescription is physician-managed and written only when your labs support it.

3

Comprehensive monitoring and support

Monthly clinical check-ins, follow-up DEXA scans and nutrition guidance, with your plan adjusted as your numbers change so you stay safe and on track throughout your weight loss journey.

4

Sustainable results and holistic health

The goal is not just to help you lose weight but to help you keep it off. Nutrition, protein targets and training are part of the program, so it fits into your wider health plan and supports your metabolic health.

Book your Therapy Entry visit

Manhattan, Bellmore or Stony Brook. No account needed.

Therapy Entry VisitConsult, DEXA scan and full blood panel
$179
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★ 4.8 on GoogleHSA / FSA eligibleNo insurance needed

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